Brain Chemical Reduces Anxiety, Increases Survival Of New Cells

May 13, 2009, The Journal of Neuroscience.

Extracts: (This study suggests)… the important role for fibroblast growth factor 2 (FGF2), a chemical important in brain development, in anxiety…Previous human studies led by the senior author, Huda Akil, PhD, at the University of Michigan and her collaborators in the Pritzker Consortium, showed that people with severe depression had low levels of FGF2 and other related chemicals….a new study, led by Javier Perez, PhD, also at the University of Michigan, examined FGF2 levels in rats selectively bred for high or low anxiety for over 19 generations. Consistent with the human depression studies, the researchers found lower FGF2 levels in rats bred for high anxiety compared to those bred for low anxiety…The study also suggests that environmental enrichment reduces anxiety by altering FGF2...”We have discovered that FGF2 has two important new roles: it’s a genetic vulnerability factor for anxiety and a mediator for how the environment affects different individuals…”…the findings suggest that part of FGF2’s role in reducing anxiety may be due to its ability to increase the survival of new cells in a brain region called the hippocampus….“This discovery may pave the way for new, more specific treatments for anxiety that will not be based on sedation — like currently prescribed drugs — but will instead fight the real cause of the disease,” said Pier Vincenzo Piazza, MD, PhD, Director of the Neurocentre Magendie an INSERM/University of Bordeaux


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The enrichment of our environment may be, according to this article, an important factor in the treatment of anxiety and depression. Hypnotherapy can contribute to this enrichment. Using hypnosis to clarify what our desires and needs are and, in the case of those being realistic, safe and achievable aiding us in how to achieve them, can contribute to enrich our environment. Changing  our daily routines and habits can also help us improve the quality of our environment. Additionally the rehearsal, from a hypnotic state, of Cognitive Behaviour Therapy (CBT)’s re- structured thoughts and beliefs related to the quality of our environment can contribute to those sinking faster and in a easier manner into our subconscious mind.


About Anna Pons

Certificat (CPPD), Post Graduat Certificat (PGCert) i Post Graduat Diploma (PGD) en Hipnoteràpia Clínica, London College of Clinical Hypnosis (LCCH) i Universitat de West London (UWL)
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